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Fliz1 Polyclonal Antibody

CAT: 0749-ABP51351-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51351-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ZC3H8 is a Protein Coding gene. Zinc finger CCCH domain-containing protein 8 acts as a transcriptional repressor of the GATA3 promoter. Sequence-specific DNA-binding factor that binds to the 5-AGGTCTC-3 sequence within the negative cis-acting element intronic regulatory region (IRR) of the GATA3 gene (By similarity) . Component of the little elongation complex (LEC), a complex required to regulate small nuclear RNA (snRNA) gene transcription by RNA polymerase II and III (PubMed:23932780) . Induces thymocyte apoptosis when overexpressed, which may indicate a role in regulation of thymocyte homeostasis. Among its related pathways are Gene Expression and RNA Polymerase II Transcription Initiation And Promoter Clearance. GO annotations related to this gene include poly (A) RNA binding and sequence-specific DNA binding. An important paralog of this gene is ZC3H4.
Description
Rabbit Anti-Fliz1 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
ZC3H8; ZC3HDC8; Zinc finger CCCH domain-containing protein 8
Gene ID
84524
Accession Number
Q8N5P1
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human Fliz1 at AA range: 50-130
Clonality
Polyclonal
Tag
Zinc finger CCCH domain-containing protein 8
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
40kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Fliz1 Polyclonal Antibody detects endogenous levels of Fliz1 protein.
Observed Molecular Weight
40
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
ZC3H8; ZC3HDC8; Zinc finger CCCH domain-containing protein 8
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q8N5P1
Isotype
Rabbit IgG

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