Ezrin Polyclonal Antibody

• Background :

  The cytoplasmic peripheral membrane protein encoded by EZR functions as a protein-tyrosine kinase substrate in microvilli. As a member of the ERM protein family, this protein serves as an intermediate between the plasma membrane and the actin cytoskeleton. This protein plays a key role in cell surface structure adhesion, migration and organization, and it has been implicated in various human cancers. A pseudogene located on chromosome 3 has been identified for EZR. Alternatively spliced variants have also been described for EZR.

• Description :

  Rabbit Anti-Ezrin Polyclonal Antibody

• Product Name Alternative :

  EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81

• Gene ID :

  7430

• Accession Number :

  P15311

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from the C-terminal region of human Ezrin at AA range: 480-560

• Clonality :

  Polyclonal

• Tag :

  Ezrin

• Applications :

  WB, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  70kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  Ezrin Polyclonal Antibody detects endogenous levels of Ezrin protein.

• Observed Molecular Weight :

  70

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:20000; IF 1:50-200

• Other Product Names :

  EZR; VIL2; Ezrin; Cytovillin; Villin-2; p81

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P15311

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG