EAR2 Polyclonal Antibody

• Background :

  NR2F6, also known as Nuclear receptor subfamily 2 group F member 6, is a nuclear protein belonging to the nuclear hormone receptor family and NR2 subfamily with a nuclear receptor DNA-binding domain. NR2F6 is a nuclear receptor involved in action regulation of the transcription of the GNRH1 gene. It binds to the TGACCT repeat motif enhancing the renin gene and thus acting as a negative modulator of renin gene transcription. NR2F6 is required early in the development of the locus ceruleus (LC), thus in some way contributing to the regulation of the forebrain clock, at least in part, through targeted release of noradrenalin into the cortical area.

• Description :

  Rabbit Anti-EAR2 Polyclonal Antibody

• Product Name Alternative :

  NR2F6; EAR2; ERBAL2; Nuclear receptor subfamily 2 group F member 6; V-erbA-related protein 2; EAR-2

• Gene ID :

  2063

• Accession Number :

  P10588

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Synthesized peptide derived from the N-terminal region of human EAR2 at AA range: 30-110

• Clonality :

  Polyclonal

• Tag :

  Nuclear receptor subfamily 2 group F member 6

• Applications :

  WB, IHC, IF, ELISA

• Purification Method :

  The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

• Concentration :

  1 mg/ml

• Molecular Weight :

  42kD

• Precautions :

  The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.

• Shipping Conditions :

  Gel pack with blue ice.

• Storage Conditions :

  Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

• Notes :

  EAR2 Polyclonal Antibody detects endogenous levels of EAR2 protein.

• Observed Molecular Weight :

  42

• Formulation :

  Liquid solution

• Buffer pH :

  Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

• Applications Notes :

  Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.

• Other Product Names :

  NR2F6; EAR2; ERBAL2; Nuclear receptor subfamily 2 group F member 6; V-erbA-related protein 2; EAR-2

• Tested Applications :

  WB, IHC, IF, IP, ELISA

• Host or Source :

  Rabbit

• Accession Number URL :

  http://www.uniprot.org/uniprot/P10588

• CAS Number :

  9007-83-4

• Isotype :

  Rabbit IgG