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DTMP Kinase Polyclonal Antibody

CAT: 0749-ABP51206-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP51206-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Thymidylate kinase (DTYMK) catalyzes the phosphorylation of dTMP to form dTDP in the dTTP synthesis pathway for DNA synthesis. DTYMK is essential for DNA synthesis and is an important intermediate enzyme in the pathway of many pyrimidine analog drugs, including 5-Fluorouracil (5-FU), the chemotherapeutic drug of choice for several solid tumors. The human DTYMK gene was isolated via functional complementation of a Saccharomyces cerevisiae cell cycle mutant, cdc8. DTYMK mRNA levels and enzyme activities are regulated at the level of cell cycle and cell growth pathways.
Description
Rabbit Anti-dTMP Kinase Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
DTYMK; CDC8; TMPK; TYMK; Thymidylate kinase; dTMP kinase
Gene ID
1841
Accession Number
P23919
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human dTMP Kinase at AA range: 1-80
Clonality
Polyclonal
Tag
Thymidylate kinase
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
22kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
DTMP Kinase Polyclonal Antibody detects endogenous levels of dTMP Kinase protein.
Observed Molecular Weight
22
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200
Other Product Names
DTYMK; CDC8; TMPK; TYMK; Thymidylate kinase; dTMP kinase
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P23919
Isotype
Rabbit IgG

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