Products for Research Use Only
RegisterLogin

Cystatin B Polyclonal Antibody

CAT: 0749-ABP51120-01Size: 30 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0749-ABP51120-01Size:30 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1) . One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies.
Description
Rabbit Anti-Cystatin B Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CSTB; CST6; STFB; Cystatin-B; CPI-B; Liver thiol proteinase inhibitor; Stefin-B
Gene ID
1476
Accession Number
P04080
Reactivity
Human, Rat
Immunogen
Synthesized peptide derived from the Internal region of human Cystatin B at AA range: 20-100
Clonality
Polyclonal
Tag
Cystatin-B
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
11kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Cystatin B Polyclonal Antibody detects endogenous levels of Cystatin B protein.
Observed Molecular Weight
11
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
CSTB; CST6; STFB; Cystatin-B; CPI-B; Liver thiol proteinase inhibitor; Stefin-B
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P04080
Isotype
Rabbit IgG

Related Products

CatalogName
ABP51119-01Cystatin A Polyclonal Antibody
ABP58319-01Cystatin A Polyclonal Antibody
ABP53875-01Cystatin SA Polyclonal Antibody
ABP51121-01Cystatin C Polyclonal Antibody
ABP53872-01Cystatin SN Polyclonal Antibody
ABP53742-01Cystatin L1 Polyclonal Antibody
ABP51118-01Cystatin 11 Polyclonal Antibody
ABP53416-01Cystatin 8 Polyclonal Antibody
ABP53877-01Cystatin E/M Polyclonal Antibody
ABP55531-01PDGF-B Polyclonal Antibody

Alternative Products

CatalogName
JOT-AP02444-01Cystatin A Polyclonal Antibody
JOT-AP02450-01Cystatin SA Polyclonal Antibody
JOT-AP02449-01Cystatin L1 Polyclonal Antibody
JOT-AP02441-01Cystatin 11 Polyclonal Antibody
MBS2005513-01Polyclonal Antibody to Cystatin A (CSTA)
BT-AP15163-01Cystatin B Polyclonal Antibody
APR05514GPolyclonal Cystatin B Antibody
NBP1-86989Rabbit Polyclonal Cystatin A Antibody

Popular Products