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Choactase Polyclonal Antibody

CAT: 0749-ABP50976-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP50976-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CHAT encodes an enzyme which catalyzes the biosynthesis of the neurotransmitter acetylcholine. CHAT product (choline O-acetyltransferase) is a characteristic feature of cholinergic neurons, and changes in these neurons may explain some of the symptoms of Alzheimer's disease. Polymorphisms in CHAT have been associated with Alzheimer's disease and mild cognitive impairment. Mutations in CHAT are associated with congenital myasthenic syndrome associated with episodic apnea. Multiple transcript variants encoding different isoforms have been found for CHAT, and some of these variants have been shown to encode more than one isoform.
Description
Rabbit Anti-Choactase Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CHAT; Choline O-acetyltransferase; CHOACTase; ChAT; Choline acetylase
Gene ID
1103
Accession Number
P28329
Reactivity
Human, Mouse, Rat
Immunogen
Synthesized peptide derived from the Internal region of human Choactase
Clonality
Polyclonal
Tag
Choline O-acetyltransferase
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
82,70kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
Choactase Polyclonal Antibody detects endogenous levels of Choactase protein.
Observed Molecular Weight
82,70
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
CHAT; Choline O-acetyltransferase; CHOACTase; ChAT; Choline acetylase
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P28329
Isotype
Rabbit IgG

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