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CEP170 Polyclonal Antibody

CAT: 0749-ABP50950-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP50950-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The product of CEP170 is a component of the centrosome, a non-membraneous organelle (centrosomal protein 170) that functions as the major microtubule-organizing center in animal cells. During interphase, the encoded protein localizes to the sub-distal appendages of mature centrioles, which are microtubule-based structures thought to help organize centrosomes. During mitosis, the protein associates with spindle microtubules near the centrosomes. The protein interacts with and is phosphorylated by polo-like kinase 1, and functions in maintaining microtubule organization and cell morphology. The human genome contains a putative transcribed pseudogene. Several alternatively spliced transcript variants of CEP170 have been found, but the full-length nature of some of these variants has not been determined.
Description
Rabbit Anti-CEP170 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CEP170; FAM68A; KAB; KIAA0470; Centrosomal protein of 170 kDa; Cep170; KARP-1-binding protein; KARP1-binding protein
Gene ID
9859
Accession Number
Q5SW79
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human CEP170 at AA range: 670-750
Clonality
Polyclonal
Tag
Centrosomal protein of 170 kDa
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
160kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CEP170 Polyclonal Antibody detects endogenous levels of CEP170 protein.
Observed Molecular Weight
160
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
CEP170; FAM68A; KAB; KIAA0470; Centrosomal protein of 170 kDa; Cep170; KARP-1-binding protein; KARP1-binding protein
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q5SW79
Isotype
Rabbit IgG

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