CdkL4 Polyclonal Antibody

CAT: 0749-ABP50946-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP50946-01Size:30 µL
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Background
Cell cycle progression is controlled in part by a family of cyclin proteins and cyclin dependent kinases (Cdks) . Cdk proteins work in concert with the cyclins to phosphorylate key substrates involved in each phase of cell cycle progression. Another family of proteins, Cdk inhibitors, also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity. Cdks are considered potential targets for anti-cancer therapy due to their involvement with cell cycle regulation. Cdks are also involved in the regulation of transcription and mRNA processing. CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation.
Description
Rabbit Anti-CdkL4 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CDKL4; Cyclin-dependent kinase-like 4
Gene ID
344387
Accession Number
Q5MAI5
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of human CdkL4 at AA range: 240-320
Clonality
Polyclonal
Tag
Cyclin-dependent kinase-like 4
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
36kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CdkL4 Polyclonal Antibody detects endogenous levels of CdkL4 protein.
Observed Molecular Weight
36
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:40000; Not yet tested in other applications.
Other Product Names
CDKL4; Cyclin-dependent kinase-like 4
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q5MAI5
Isotype
Rabbit IgG

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