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CD1e Polyclonal Antibody

CAT: 0749-ABP50901-01Size: 30 µLDry Ice: NoHazardous: No
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CAT#:0749-ABP50901-01Size:30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
CD1E encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein (CD1e molecule) encoded by CD1E localizes within Golgi compartments, endosomes, and lysosomes, and is cleaved into a stable soluble form. The soluble form is required for the intracellular processing of some glycolipids into a form that can be presented by other CD1 family members. Many alternatively spliced transcript variants encoding different isoforms have been described. Additional transcript variants have been found; however, their biological validity has not been determined.
Description
Rabbit Anti-CD1e Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
CD1E; T-cell surface glycoprotein CD1e; membrane-associated; hCD1e; R2G1; CD antigen CD1e
Gene ID
913
Accession Number
P15812
Reactivity
Human
Immunogen
Synthesized peptide derived from the Internal region of human CD1e at AA range: 190-270
Clonality
Polyclonal
Tag
T-cell surface glycoprotein CD1e membrane-associated
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
36kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CD1e Polyclonal Antibody detects endogenous levels of CD1e protein.
Observed Molecular Weight
36
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
CD1E; T-cell surface glycoprotein CD1e; membrane-associated; hCD1e; R2G1; CD antigen CD1e
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P15812
Isotype
Rabbit IgG

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