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CD179b Polyclonal Antibody

CAT: 0749-ABP50899-01Size: 30 µLDry Ice: NoHazardous: No
CAT#: ABP50899-01Size: 30 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. IGLL1 does not undergo rearrangement. Mutations in IGLL1 can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for IGLL1.
Description
Rabbit Anti-CD179b Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
IGLL1; IGL1; Immunoglobulin lambda-like polypeptide 1; CD179 antigen-like family member B; Ig lambda-5; Immunoglobulin omega polypeptide; Immunoglobulin-related protein 14.1; CD antigen CD179b; IGLC1; Ig lambda-1 chain C regions; IGLC2; Ig
Gene ID
3543
Accession Number
P15814/P0CG04/P0CG05/P0CG06/P0CF74/A0M8Q6
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the N-terminal region of human CD179b
Clonality
Polyclonal
Tag
Immunoglobulin lambda-like polypeptide 1
Applications
WB, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
23kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CD179b Polyclonal Antibody detects endogenous levels of CD179b protein.
Observed Molecular Weight
23
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; ELISA 1:10000; Not yet tested in other applications.
Other Product Names
IGLL1; IGL1; Immunoglobulin lambda-like polypeptide 1; CD179 antigen-like family member B; Ig lambda-5; Immunoglobulin omega polypeptide; Immunoglobulin-related protein 14.1; CD antigen CD179b; IGLC1; Ig lambda-1 chain C regions; IGLC2; Ig
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/P15814
Isotype
Rabbit IgG

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