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CCP2 Polyclonal Antibody

CAT: 0749-ABP50890-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP50890-01Size:30 µL
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Background
The peptidase M14 family of carboxypeptidases (CPs) are involved in various functions throughout the body which include digestion of food and biosynthesis of peptides that function in intercellular signaling. CCP2 (cytosolic carboxypeptidase 2), also known as AGBL2 (ATP/GTP binding protein-like 2), is a 902 amino acid cytoplasmic protein belonging to the peptidase M14 family. CCP2 is considered a metallocarboxypeptidase that may play a role in the processing of tubulin. CCP2 binds one zinc ion per subunit as a cofactor and exists as three alternatively spliced isoforms. The gene encoding CCP2 is located on human chromosome 11p11.2. Chromosome 11 houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.
Description
Rabbit Anti-CCP2 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
AGBL2; CCP2; Cytosolic carboxypeptidase 2; ATP/GTP-binding protein-like 2
Gene ID
79841
Accession Number
Q5U5Z8
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the C-terminal region of human CCP2 at AA range: 700-780
Clonality
Polyclonal
Tag
Cytosolic carboxypeptidase 2
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
104kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
CCP2 Polyclonal Antibody detects endogenous levels of CCP2 protein.
Observed Molecular Weight
104
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:40000; IF 1:50-200
Other Product Names
AGBL2; CCP2; Cytosolic carboxypeptidase 2; ATP/GTP-binding protein-like 2
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q5U5Z8
Isotype
Rabbit IgG

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