ANKRD30A Polyclonal Antibody

CAT: 0749-ABP50654-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP50654-01Size:30 µL
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Background
Ankyrins are membrane adaptor molecules that play important roles in coupling integral membrane proteins to the spectrin-based cytoskeleton network. Mutations of ankyrin genes lead to severe genetic diseases, such as fatal cardiac arrhythmias and hereditary spherocytosis. ANKRD30A (ankyrin repeat domain 30A), also known as serologically defined breast cancer antigen NY-BR-1, is a 1,397 amino acid coiled-coil protein. Containing six ANK repeats and thirty-seven exons, ANKRD30A is a distant homolog of the POTE family. Initiated by either Dnmt1 or Met-57, ANKRD30A is highly expressed in breast and testis, and faintly in placenta. Present in 80% of breast cancers, but not in other types of tumors, ANKRD30A is a differentiation antigen and a potential target for antibody‐based therapies in breast cancers.
Description
Rabbit Anti-ANKRD30A Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
ANKRD30A; Ankyrin repeat domain-containing protein 30A; Serologically defined breast cancer antigen NY-BR-1
Gene ID
91074
Accession Number
Q9BXX3
Reactivity
Human
Immunogen
Synthesized peptide derived from the C-terminal region of human ANKRD30A at AA range: 1010-1090
Clonality
Polyclonal
Tag
Ankyrin repeat domain-containing protein 30A
Applications
WB, IHC, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
153kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
ANKRD30A Polyclonal Antibody detects endogenous levels of ANKRD30A protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:5000; IF 1:50-200
Other Product Names
ANKRD30A; Ankyrin repeat domain-containing protein 30A; Serologically defined breast cancer antigen NY-BR-1
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q9BXX3
Isotype
Rabbit IgG

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