ADCK5 Polyclonal Antibody

CAT: 0749-ABP50604-01Size: 30 µLDry Ice: NoHazardous: No
CAT#:0749-ABP50604-01Size:30 µL
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Background
CABC1 (chaperone activity of bc1 complex-like), also known as COQ8 or ADCK3 (aarF domain-containing protein kinase 3) is a 647 amino acid mitochondrial protein that belongs to the ADCK protein kinase. Ubiquitously expressed with higher expression in heart and skeletal muscle, CABC1 is thought to function as a chaperone in the proper assembly of protein complexes found in the respiratory chain. CABC1 expression is induced both in response to DNA damage and by the tumor suppressor p53. When CABC1 expression is inhibited, p53-induced apoptosis is partially suppressed, suggesting a possible role for CABC1 in tumor suppression. Mutations in the gene encoding CABC1 may be implicated in ubiquinone deficiency which can lead to cerebellar ataxia and seizures. Four isoforms of CABC1 exist due to alternative splicing events. Other members of the ADCK protein kinase family include ADCK1, ADCK2, ADCK4 and ADCK5.
Description
Rabbit Anti-ADCK5 Polyclonal Antibody
CAS Number
9007-83-4
Product Name Alternative
ADCK5; Uncharacterized aarF domain-containing protein kinase 5
Gene ID
203054
Accession Number
Q3MIX3
Reactivity
Human, Mouse
Immunogen
Synthesized peptide derived from the Internal region of human ADCK5 at AA range: 120-200
Clonality
Polyclonal
Tag
Uncharacterized aarF domain-containing protein kinase 5
Applications
WB, IF, ELISA
Purification Method
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration
1 mg/ml
Molecular Weight
66kD
Precautions
The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Shipping Conditions
Gel pack with blue ice.
Storage Conditions
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Notes
ADCK5 Polyclonal Antibody detects endogenous levels of ADCK5 protein.
Formulation
Liquid solution
Buffer pH
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Applications Notes
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000; IF 1:200-1:1000; ELISA 1:20000; Not yet tested in other applications.
Other Product Names
ADCK5; Uncharacterized aarF domain-containing protein kinase 5
Tested Applications
WB, IHC, IF, IP, ELISA
Host or Source
Rabbit
Accession Number URL
http://www.uniprot.org/uniprot/Q3MIX3
Isotype
Rabbit IgG

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