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Oxyfluorfen

CAT: 0804-HY-119176-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-119176-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Oxyfluorfen is a pre- and post-emergence diphenyl ether herbicide to control annual broad-leaved and grass weeds. Oxyfluorfen is a protoporphyrinogen oxidase inhibitor and inhibits photosynthesis by blocking chlorophyll synthesis. Oxyfluorfen can inhibit cell growth. Oxyfluorfen induces DNA damage and exhibits toxicity toward aquatic organisms such as Paramisgurnus dabryanus. Oxyfluorfen has genome-level deleterious effects on fish that can lead to stunted skeletal growth. Oxyfluorfen induces transverse limb deficiency or craniosynostosis[1][2].
CAS Number
42874-03-3
UNSPSC
12352005
Hazard Statement
H400, H410
Target
Herbicide; Protoporphyrinogen IX oxidase
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/oxyfluorfen.html
Concentration
10mM
Purity
99.69
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
FC(C1=CC=C(OC2=CC=C([N+]([O-])=O)C(OCC)=C2)C(Cl)=C1)(F)F
Molecular Formula
C15H11ClF3NO4
Molecular Weight
361.70
Precautions
H400, H410
References & Citations
[1]Chi Wu, et al. Sorption, Degradation and Bioavailability of Oxyfluorfen in Biochar-Amended Soils. Sci Total Environ. 2019 Mar 25;658:87-94.|[2]E Warabi, et al. Resistance of a Soybean Cell Line to Oxyfluorfen by Overproduction of Mitochondrial Protoporphyrinogen Oxidase. Pest Manag Sci. 2001 Aug;57 (8) :743-8.|[3]F. Peixoto, et al., Toxicological effects of oxyfluorfen on oxidative stress enzymes in tilapia Oreochromis niloticus, Pesticide Biochemistry and Physiology, Volume 85, Issue 2, 2006, Pages 91-96, ISSN 0048-3575.|[4]Stagg, N. J., et al., (2012) . Assessment of possible carcinogenicity of oxyfluorfen to humans using mode of action analysis of rodent liver effects. Toxicological sciences: an official journal of the Society of Toxicology, 128 (2), 334–345.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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