RAB14 rabbit pAb

CAT: 0855-ES11931-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES11931-01Size:50 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]) .[supplied by OMIM, Mar 2009]
Description
RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al. 2004 [PubMed 15004230]). [supplied by OMIM, Mar 2009],
UniProt
P61106
Swiss Prot
P61106
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from part region of human protein
Target
RAB14
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
23kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
23kD
Fragment
IgG
Subcellular Location
Recycling endosome . Early endosome membrane ; Lipid-anchor ; Cytoplasmic side . Golgi apparatus membrane ; Lipid-anchor ; Cytoplasmic side . Golgi apparatus, trans-Golgi network membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, phagosome . Recruited to recycling endosomes by DENND6A (PubMed:22595670) . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211) . .
Gene ID (Human)
51552

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