RAB14 rabbit pAb

• Background:

  RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al., 2004 [PubMed 15004230]) .[supplied by OMIM, Mar 2009]

• Description:

  RAB14 belongs to the large RAB family of low molecular mass GTPases that are involved in intracellular membrane trafficking. These proteins act as molecular switches that flip between an inactive GDP-bound state and an active GTP-bound state in which they recruit downstream effector proteins onto membranes (Junutula et al. 2004 [PubMed 15004230]). [supplied by OMIM, Mar 2009],

• UniProt:

  P61106

• Swiss Prot:

  P61106

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from part region of human protein

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight:

  23kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  23kD

• Fragment:

  IgG

• Subcellular Location:

  Recycling endosome . Early endosome membrane ; Lipid-anchor ; Cytoplasmic side . Golgi apparatus membrane ; Lipid-anchor ; Cytoplasmic side . Golgi apparatus, trans-Golgi network membrane ; Lipid-anchor ; Cytoplasmic side . Cytoplasmic vesicle, phagosome . Recruited to recycling endosomes by DENND6A (PubMed:22595670) . Recruited to phagosomes containing S.aureus or M.tuberculosis (PubMed:21255211) . .

• Gene ID (Human):

  51552