KA2507

KA2507

• CAS Number: 1636894-46-6
• UNSPSC Description: KA2507 is a potent, orally active and selective HDAC6 inhibitor, with an IC50 of 2.5 nM. KA2507 shows antitumor activities and immune modulatory effects in preclinical models[1].
• Target Antigen: HDAC
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage;Epigenetics
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/ka2507.html
• Smiles: O=C(NO)C1=CC=C(CN(C2=NC=CN=C2)C3=NC=CN=C3)C=C1
• Molecular Weight: 322.32
• References & Citations: [1]Apostolia M Tsimberidou, et al. Preclinical Development and First-in-Human Study of KA2507, a Selective and Potent Inhibitor of Histone Deacetylase 6, for Patients with Refractory Solid Tumors. Clin Cancer Res. 2021 May 4.
• Shipping Conditions: Room Temperature