STAB2 rabbit pAb

CAT: 0855-ES11201-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES11201-01Size:50 µL
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Background
This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF) -like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008]
Description
This gene encodes a large, transmembrane receptor protein which may function in angiogenesis, lymphocyte homing, cell adhesion, or receptor scavenging. The protein contains 7 fasciclin, 15 epidermal growth factor (EGF)-like, and 2 laminin-type EGF-like domains as well as a C-type lectin-like hyaluronan-binding Link module. The protein is primarily expressed on sinusoidal endothelial cells of liver, spleen, and lymph node. The receptor has been shown to bind and endocytose ligands such as hyaluronan, low density lipoprotein, Gram-positive and Gram-negative bacteria, and advanced glycosylation end products. Supporting its possible role as a scavenger receptor, the protein has been shown to cycle between the plasma membrane and lysosomes. [provided by RefSeq, Jul 2008],
UniProt
Q8WWQ8
Swiss Prot
Q8WWQ8
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 980-1060
Target
STAB2
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF
Concentration
1 mg/ml
Dilution
IHC-p 1:50-300 IF 1:100-300 Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
280kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
280kD
Fragment
IgG
Subcellular Location
Cell membrane ; Single-pass type I membrane protein . Cytoplasm . Only a small amount appears to be present at the cell surface (PubMed:17145755) .
Gene ID (Human)
55576

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