ITLN1 rabbit pAb

ITLN1 rabbit pAb

• Description: Developmental stage: Found in fetal small intestine and thymus. function: Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism. mass spectrometry: PubMed: 17621593, PTM: N-glycosylated. similarity: Contains 1 fibrinogen C-terminal domain. subcellular location: Enriched in lipid rafts. subunit: Homotrimer; disulfide-linked. tissue specificity: Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus.
• Gene ID: 55600
• UniProt: Q8WWA0
• Cellular Locus: Cell membrane ; Lipid-anchor, GPI-anchor. Secreted. Enriched in lipid rafts..
• Host: Rabbit
• Species Reactivity: Human, Rat, Mouse,
• Immunogen: Synthesized peptide derived from human protein . at AA range: 110-190
• Clonality: Polyclonal
• Validated Applications: WB, ELISA
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: WB 1:500-2000 ELISA 1:5000-20000
• Molecular Weight: 34kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.