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CHSTF rabbit pAb

CAT: 0855-ES11175-02Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0855-ES11175-02Size:100 µL
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Background
Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012]
Description
Chondroitin sulfate (CS) is a glycosaminoglycan which is an important structural component of the extracellular matrix and which links to proteins to form proteoglycans. Chondroitin sulfate E (CS-E) is an isomer of chondroitin sulfate in which the C-4 and C-6 hydroxyl groups are sulfated. This gene encodes a type II transmembrane glycoprotein that acts as a sulfotransferase to transfer sulfate to the C-6 hydroxal group of chondroitin sulfate. This gene has also been identified as being co-expressed with RAG1 in B-cells and as potentially acting as a B-cell surface signaling receptor. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2012],
UniProt
Q7LFX5
Swiss Prot
Q7LFX5
Reactivity
Human; Rat; Mouse
Immunogen
Synthesized peptide derived from human protein . at AA range: 440-520
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Molecular Weight
61kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
61kD
Fragment
IgG
Subcellular Location
Golgi apparatus membrane ; Single-pass type II membrane protein . A small fraction may also be present at the cell surface, where it acts as a B-cell receptor.
Gene ID (Human)
51363

UniProtKB · Q7LFX5

Carbohydrate sulfotransferase 15

CHSTF_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q7LFX5
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CHST15
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
2.8.2.33
Processing
—
Secondary accessions
O60338, O60474, Q86VM4
Protein keywords

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoprotein

Cellular component

Golgi apparatusMembrane

Technical term

Proteomics identificationReference proteome

Domain

Signal-anchorTransmembraneTransmembrane helix

Molecular function

Transferase

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