VASN rabbit pAb

CAT: 0855-ES10988-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES10988-01Size:50 µL
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Background
Function:May act as an inhibitor of TGF-beta signaling., PTM:N-glycosylated., similarity:Contains 1 EGF-like domain., similarity:Contains 1 fibronectin type-III domain., similarity:Contains 11 LRR (leucine-rich) repeats., subunit:Interacts with TGFB1, TGFB2 and TGFB3., tissue specificity:Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.
Description
Function: May act as an inhibitor of TGF-beta signaling. PTM: N-glycosylated. similarity: Contains 1 EGF-like domain. similarity: Contains 1 fibronectin type-III domain. similarity: Contains 11 LRR (leucine-rich) repeats. subunit: Interacts with TGFB1, TGFB2 and TGFB3. tissue specificity: Expressed at highest levels in aorta, at intermediate levels in kidney and placenta and at lowest levels in brain, heart, liver, lung and skeletal muscle. Within the aorta, the strongest expression is found in the tunica media of the proximal ascending aorta, the descending thoracic aorta, the abdominal aorta and the coronary arteries. Within the kidney, expression is found in the interstitial cells.
UniProt
Q6EMK4
Swiss Prot
Q6EMK4
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from part region of human protein
Target
VASN
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000 ELISA 1:5000-20000
Buffer
-20°C/1 year
Molecular Weight
74kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
74kD
Fragment
IgG
Subcellular Location
Membrane ; Single-pass type I membrane protein . Secreted .
Gene ID (Human)
114990

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