Tenifatecan

CAT: 0804-HY-14871-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-14871-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Tenifatecan (SN2310) is an injectable emulsion composed of vitamin E, a succinate derivative, as well as 7-ethyl-10-hydroxycamptothecin (SN-38, the active metabolite of irinotecan) . Tenifatecan (SN2310) possesses anticancer activity[1].

CAS Number

850728-18-6

Product Name Alternative

SN2310

UNSPSC

12352005

Hazard Statement

H301

Target

Topoisomerase

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/tenifatecan.html

Solubility

10 mM in DMSO

Smiles

CCC1=C2C(C(N3C2)=CC([C@](O)(C(OC4)=O)CC)=C4C3=O)=NC5=CC=C(OC(CCC(OC6=C(C)C(C)=C(O[C@@](C)(CC7)CCC[C@H](C)CCC[C@H](C)CCCC(C)C)C7=C6C)=O)=O)C=C51

Molecular Formula

C55H72N2O9

Molecular Weight

905.17

Precautions

P264-P270-P330-P405-P501

References & Citations

[1]Jean-Francois Marier, et al. Pharmacokinetics of SN2310, an injectable emulsion that incorporates a new derivative of SN-38 in patients with advanced solid tumors. J Pharm Sci. 2011 Oct;100 (10) :4536-45.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

Phase 1

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