Petadeferitrin

CAT: 0804-HY-16912-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-16912-01Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Petadeferitrin (SP-420) is a tridentate iron chelator belonging to the class of iron chelators, with orally activity. Petadeferitrin can be used in research related to β-thalassemia[1][2][3].

CAS Number

911714-45-9

Product Name Alternative

SP-420

UNSPSC

12352005

Target

Ferroptosis

Type

Reference compound

Related Pathways

Apoptosis

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/SP-420.html

Purity

99.71

Solubility

DMSO : ≥ 38 mg/mL

Smiles

O=C([C@]1(C)N=C(C2=CC=C(OCCOCCOC)C=C2O)SC1)O

Molecular Formula

C16H21NO6S

Molecular Weight

355.41

References & Citations

[1]Bergeron RJ, et al. Substituent effects on desferrithiocin and desferrithiocin analogue iron-clearing and toxicity profiles. J Med Chem. 2012 Aug 23;55 (16) :7090-103.|[2]Basu S, et al. Understanding the intricacies of iron overload associated with β-thalassemia: a comprehensive review[J]. Thalassemia Reports, 2023, 13 (3) : 179-194.|[3]Taher A T, et al. Safety and pharmacokinetics of the oral iron chelator SP‐420 in β‐thalassemia[J]. American Journal of Hematology, 2017, 92 (12) : 1356-1361.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

Phase 2

Petadeferitrin

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