CD70 rabbit pAb

• Background:

  The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008]

• Description:

  The protein encoded by this gene is a Cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This Cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This Cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis. [provided by RefSeq, Jul 2008],

• UniProt:

  P32970

• Swiss Prot:

  P32970

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthetic peptide from human protein at AA range: 150-193

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  IHC-p 1:50-200, ELISA 1:10000-20000

• Storage Conditions:

  -20°C/1 year

• Fragment:

  IgG

• Subcellular Location:

  Membrane ; Single-pass type II membrane protein .

• Other Product Names:

  CD70 antigen (CD27 ligand; CD27-L; Tumor necrosis factor ligand superfamily member 7; CD antigen CD70)

• Gene ID (Human):

  970