BMP-9 rabbit pAb

• Background:

  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016]

• Description:

  This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate each subunit of the disulfide-linked homodimer. This protein regulates cartilage and bone development, angiogenesis and differentiation of cholinergic central nervous system neurons. Mutations in this gene are associated with hereditary hemorrhagic telangiectasia. [provided by RefSeq, Jul 2016],

• UniProt:

  Q9UK05

• Swiss Prot:

  Q9UK05

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthetic peptide from human protein at AA range: 371-420

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  IHC; IF; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  IHC-p 1:50-200, ELISA 1:10000-20000

• Storage Conditions:

  -20°C/1 year

• Fragment:

  IgG

• Subcellular Location:

  Secreted .

• Other Product Names:

  Growth/differentiation factor 2 (GDF-2; Bone morphogenetic protein 9; BMP-9)

• Gene ID (Human):

  2658