PDGF-C rabbit pAb

CAT: 0855-ES8707-01Size: 50 µLDry Ice: NoHazardous: No
CAT#:0855-ES8707-01Size:50 µL
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Background
Platelet derived growth factor C (PDGFC) Homo sapiens The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010]
Description
Platelet derived growth factor C (PDGFC) Homo sapiens The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a core motif of eight cysteines. This gene product appears to form only homodimers. It differs from the platelet-derived growth factor alpha and beta polypeptides in having an unusual N-terminal domain, the CUB domain. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2010],
UniProt
Q9NRA1
Swiss Prot
Q9NRA1
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic peptide from human protein at AA range: 61-110
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm, cytosol . Secreted . Nucleus . Cytoplasmic granule . Cell membrane . Sumoylated form is predominant in the nucleus (PubMed:15247255) . Stored in alpha granules in platelets (PubMed:15061151) . .
Other Product Names
Platelet-derived growth factor C (PDGF-C; Fallotein; Spinal cord-derived growth factor; SCDGF; VEGF-E) [Cleaved into: Platelet-derived growth factor C, latent form (PDGFC latent form) ; Platelet-derived growth factor C, receptor-binding form (PDGFC receptor-binding form) ]
Gene ID (Human)
56034

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