Flt-4 rabbit pAb

• Description:

  This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type IA. [provided by RefSeq, Jul 2008],

• Synonyms:

  Vascular endothelial growth factor receptor 3 (VEGFR-3;EC 2.7.10.1;Fms-like tyrosine kinase 4;FLT-4;Tyrosine-protein kinase receptor FLT4)

• Gene ID:

  2324

• UniProt:

  P35916

• Cellular Locus:

  Cell membrane ; Single-pass type I membrane protein. Cytoplasm. Nucleus. Ligand-mediated autophosphorylation leads to rapid internalization..; [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Ligand-mediated autophosphorylation leads to rapid internalization.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Secreted. Cytoplasm.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Synthetic peptide from human protein at AA range: 640-700

• Clonality:

  Polyclonal

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000

• Molecular Weight:

  170kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.