Histone H2B (Acetyl Lys21) rabbit pAb

• Background:

  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015]

• Description:

  Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element. [provided by RefSeq, Aug 2015],

• Synonyms:

  H2BFS; Histone H2B type F-S; Histone H2B.s; H2B/s;H2BK21AC

• Gene ID:

  255626

• UniProt:

  Q96A08/P33778/P62807

• Cellular Locus:

  Nucleus. Chromosome.

• Host:

  Rabbit

• Species Reactivity:

  Human, Rat, Mouse

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Synthetic Acetyl peptide from human protein at AA range: 21

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, ELISA

• Validated Applications:

  WB, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-2000, ELISA 1:10000-20000

• Molecular Weight:

  15kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  15 kD

• Subcellular Location:

  Nucleus . Chromosome .

• Other Product Names:

  H2BFS; Histone H2B type F-S; Histone H2B.s; H2B/s; H2BK21AC

• Gene ID (Human):

  255626

• SwissProt (Human):

  Q96A08/P33778/P62807