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GABARAP rabbit pAb

CAT: 0855-ES8482-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8482-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the MAP1 LC3 family., subunit:Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin (By similarity) . Interacts with ULK1., tissue specificity:Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.
Description
Function: Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the MAP1 LC3 family. subunit: Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin (By similarity). Interacts with ULK1. tissue specificity: Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.
Product Name Alternative
GABA (A) receptor-associated protein-like 2
UniProt
P60520
Swiss Prot
P60520
Reactivity
Human; Mouse; Rat
Immunogen
Synthetic Peptide of GABARAP AA range: 26-75
Target
GABARAP
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
WB 1:500-2000, ELISA 1:10000-20000
Buffer
-20°C/1 year
Molecular Weight
17kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
17kD
Fragment
IgG
Subcellular Location
Cytoplasmic vesicle, autophagosome . Endoplasmic reticulum membrane . Golgi apparatus .
Other Product Names
GABA (A) receptor-associated protein-like 2
Gene ID (Human)
11345

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