GABARAP rabbit pAb

• Background :

  Function:Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the MAP1 LC3 family., subunit:Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin (By similarity) . Interacts with ULK1., tissue specificity:Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.

• Description :

  Function: Involved in intra-Golgi traffic. Modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. It first stimulates the ATPase activity of NSF which in turn stimulates the association with GOSR1. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. similarity: Belongs to the MAP1 LC3 family. subunit: Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin (By similarity). Interacts with ULK1. tissue specificity: Ubiquitous. Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle. Expressed at very low levels in lung, thymus and small intestine.

• Product Name Alternative :

  GABA (A) receptor-associated protein-like 2

• UniProt :

  P60520

• Swiss Prot :

  P60520

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthetic Peptide of GABARAP AA range: 26-75

• Target :

  GABARAP

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000, ELISA 1:10000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  17kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  17kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasmic vesicle, autophagosome . Endoplasmic reticulum membrane . Golgi apparatus .

• Other Product Names :

  GABA (A) receptor-associated protein-like 2

• Gene ID (Human) :

  11345