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FOG-2 rabbit pAb

CAT: 0855-ES8410-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES8410-01Size:50 µL
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Background
Zinc finger protein, FOG family member 2 (ZFPM2) Homo sapiens The zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq, Jul 2008]
Description
Zinc finger protein, FOG family member 2 (ZFPM2) Homo sapiens The Zinc finger protein encoded by this gene is a widely expressed member of the FOG family of transcription factors. The family members modulate the activity of GATA family proteins, which are important regulators of hematopoiesis and cardiogenesis in mammals. It has been demonstrated that the protein can both activate and down-regulate expression of GATA-target genes, suggesting different modulation in different promoter contexts. A related mRNA suggests an alternatively spliced product but this information is not yet fully supported by the sequence. [provided by RefSeq, Jul 2008],
UniProt
Q8WW38
Swiss Prot
Q8WW38
Reactivity
Human; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human ZFPM2. AA range:921-970
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
128kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
128kD
Fragment
IgG
Subcellular Location
Nucleus .
Other Product Names
ZFPM2; FOG2; ZNF89B; Zinc finger protein ZFPM2; Friend of GATA protein 2; FOG-2; Friend of GATA 2; hFOG-2; Zinc finger protein 89B; Zinc finger protein multitype 2
Gene ID (Human)
23414

UniProtKB · Q8WW38

Zinc finger protein ZFPM2

FOG2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8WW38
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
ZFPM2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q32MA6, Q9NPL7, Q9NPS4, Q9UNI5
Protein keywords

Molecular function

ActivatorDNA-bindingRepressor

Coding sequence diversity

Alternative splicing

Disease

CardiomyopathyDisease variant

Biological process

DifferentiationGonadal differentiationTranscriptionTranscription regulation

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Ligand

Metal-bindingZinc

Cellular component

Nucleus

Technical term

Proteomics identificationReference proteome

Domain

RepeatZinc-finger

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