MELK rabbit pAb
CAT:
855-ES8105-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MELK rabbit pAb
- Description: Catalytic activity: ATP + a protein = ADP + a phosphoprotein. function: Phosphorylates ZNF622 and may contribute to its redirection to the nucleus. May be involved in the inhibition of spliceosome assembly during mitosis. PTM: Autophosphorylated. Thr-478 phosphorylation during mitosis promotes interaction with PPP1R8. similarity: Belongs to the protein kinase superfamily. similarity: Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. SNF1 subfamily. similarity: Contains 1 KA1 (kinase-associated) domain. similarity: Contains 1 protein kinase domain. subunit: Interacts with ZNF622 and PPP1R8. tissue specificity: Expressed in placenta, kidney, thymus, testis, ovary and intestine.
- Synonyms: MELK; KIAA0175; Maternal embryonic leucine zipper kinase; hMELK; Protein kinase Eg3; pEg3 kinase; Protein kinase PK38; hPK38; Tyrosine-protein kinase MELK
- Gene ID: 9833
- UniProt: Q14680
- Cellular Locus: Cell membrane ; Peripheral membrane protein.
- Host: Rabbit
- Species Reactivity: Human, Rat, Mouse,
- Immunogen: The antiserum was produced against synthesized peptide derived from human MELK. AA range:431-480
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
- Molecular Weight: 75kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.