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GASP-1 rabbit pAb

CAT: 0855-ES8093-01Size: 50 µLDry Ice: NoHazardous: No
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Background
This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R) . Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010]
Description
This gene encodes a member of the GPRASP (G protein-coupled receptor associated sorting protein) family. The protein may modulate lysosomal sorting and functional down-regulation of a variety of G-protein coupled receptors. It targets receptors for degradation in lysosomes. The receptors interacting with this sorting protein include D2 dopamine receptor (DRD2), delta opioid receptor (OPRD1), beta-2 adrenergic receptor (ADRB2), D4 dopamine receptor (DRD4) and cannabinoid 1 receptor (CB1R). Multiple alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, May 2010],
Product Name Alternative
GPRASP1; GASP; KIAA0443; G-protein coupled receptor-associated sorting protein 1; GASP-1
UniProt
Q5JY77
Swiss Prot
Q5JY77
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human GASP1. AA range:741-790
Target
GASP-1
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm .
Other Product Names
GPRASP1; GASP; KIAA0443; G-protein coupled receptor-associated sorting protein 1; GASP-1
Gene ID (Human)
9737

UniProtKB · Q5JY77

G protein-coupled receptor-associated sorting protein 1

GASP1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q5JY77
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
GPRASP1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
GASP-1
EC number
—
Processing
—
Secondary accessions
O43168, Q96LA1
Protein keywords

Cellular component

Cytoplasm

PTM

Phosphoprotein

Technical term

Proteomics identificationReference proteome

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