N-CoR rabbit pAb
CAT:
855-ES8074-01
Size:
50 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
N-CoR rabbit pAb
- Description: This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20. [provided by RefSeq, Jun 2010],
- Synonyms: NCOR1; KIAA1047; Nuclear receptor corepressor 1; N-CoR; N-CoR1
- Gene ID: 9611
- UniProt: O75376
- Cellular Locus: Nucleus.
- Host: Rabbit
- Species Reactivity: Human, Mouse
- Immunogen: The antiserum was produced against synthesized peptide derived from human NCoR1. AA range:51-100
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
- Molecular Weight: 270kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.