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Neuron Navigator 1 rabbit pAb

CAT: 0855-ES7917-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES7917-01Size:50 µL
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Background
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009]
Description
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. The exact function of this gene is not known, but it is thought to play a role in in neuronal development and regeneration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2009],
UniProt
Q8NEY1
Swiss Prot
Q8NEY1
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from Neuron Navigator 1 . at AA range: 510-590
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Molecular Weight
200kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
200kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton . Associates with a subset of microtubule plus ends. Enriched in neuronal growth cones (By similarity) . .
Other Product Names
NAV1; KIAA1151; KIAA1213; POMFIL3; STEERIN1; Neuron navigator 1; Pore membrane and/or filament-interacting-like protein 3; Steerin-1; Unc-53 homolog 1; unc53H1
Gene ID (Human)
89796

UniProtKB · Q8NEY1

Neuron navigator 1

NAV1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8NEY1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
NAV1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8MS88, Q5SVH1, Q5SVH2, Q5SVH3, Q5SVH7, Q5VUY9, Q8IVL2, Q96II1, Q9H7V9, Q9H9S9, Q9H9T5, Q9UGI1, Q9ULK7, Q9ULR9
Protein keywords

PTM

AcetylationMethylationPhosphoprotein

Coding sequence diversity

Alternative splicing

Domain

Coiled coil

Cellular component

CytoplasmCytoskeletonMicrotubule

Molecular function

Developmental protein

Biological process

DifferentiationNeurogenesis

Technical term

Proteomics identificationReference proteome

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