β-1,4-Gal-T2 rabbit pAb

β-1,4-Gal-T2 rabbit pAb

• Description: This gene is one of seven beta-1, 4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1, 4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity i
• Synonyms: B4GALT2; Beta-1; 4-galactosyltransferase 2; Beta-1, 4-GalTase 2; Beta4Gal-T2; b4Gal-T2; UDP-Gal:beta-GlcNAc beta-1, 4-galactosyltransferase 2; UDP-galactose:beta-N-acetylglucosamine beta-1, 4-galactosyltransferase 2
• Gene ID: 8704
• UniProt: O60909
• Cellular Locus: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Trans cisternae of Golgi stack.
• Host: Rabbit
• Species Reactivity: Human, Mouse
• Immunogen: Synthesized peptide derived from the C-terminal region of human β-1,4-Gal-T2.
• Clonality: Polyclonal
• Validated Applications: IHC, IF, ELISA
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.