PEA-15 rabbit pAb

• Background:

  Phosphoprotein enriched in astrocytes 15 (PEA15) Homo sapiens This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

• Description:

  Phosphoprotein enriched in astrocytes 15 (PEA15) Homo sapiens This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014],

• Synonyms:

  PEA15; Astrocytic phosphoprotein PEA-15; 15 kDa phosphoprotein enriched in astrocytes; Phosphoprotein enriched in diabetes; PED

• Gene ID:

  8682

• UniProt:

  Q15121

• Cellular Locus:

  Cytoplasm. Associated with microtubules.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat, Monkey

• Reactivity:

  Human; Mouse; Rat; Monkey

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human PEA-15. AA range:81-130

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IHC, IF, ELISA

• Validated Applications:

  WB, IHC, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight:

  36kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  36 kD

• Subcellular Location:

  Cytoplasm. Associated with microtubules.

• Other Product Names:

  PEA15; Astrocytic phosphoprotein PEA-15; 15 kDa phosphoprotein enriched in astrocytes; Phosphoprotein enriched in diabetes; PED

• Gene ID (Human):

  8682

• SwissProt (Human):

  Q15121