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Urocortin rabbit pAb

CAT: 0855-ES7474-01Size: 50 µLDry Ice: NoHazardous: No
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Background
This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family. The encoded preproprotein is proteolytically processed to generate the mature peptide, an endogenous ligand for both corticotropin-releasing factor receptor 1 and corticotropin-releasing factor receptor 2. In the brain this peptide may be responsible for the effects of stress on appetite. This peptide may also play a role in mood disorders, neurodegeneration, and skeletal system disorders. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin-2. [provided by RefSeq, Feb 2016]
Description
This gene encodes a member of the sauvagine/corticotropin-releasing factor/urotensin I family. The encoded preproprotein is proteolytically processed to generate the mature peptide, an endogenous ligand for both corticotropin-releasing factor receptor 1 and corticotropin-releasing factor receptor 2. In the brain this peptide may be responsible for the effects of stress on appetite. This peptide may also play a role in mood disorders, neurodegeneration, and skeletal system disorders. In spite of the gene family name similarity, the product of this gene has no sequence similarity to urotensin-2. [provided by RefSeq, Feb 2016],
UniProt
P55089
Swiss Prot
P55089
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Urocortin. AA range:71-120
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Secreted.
Other Product Names
UCN; Urocortin
Gene ID (Human)
7349

UniProtKB · P55089

Urocortin

UCN1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P55089
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
UCN
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
Precursor
Secondary accessions
Q6FG64
Protein keywords

Technical term

3D-structureReference proteome

PTM

AmidationCleavage on pair of basic residues

Biological process

Hearing

Molecular function

Hormone

Cellular component

Secreted

Domain

Signal

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