Products for Research Use Only
RegisterLogin

CDK5 Activator-binding C48 rabbit pAb

CAT: 0855-ES6757-01Size: 50 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0855-ES6757-01Size:50 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]
Description
This gene encodes a regulator of CDK5 (cyclin-dependent kinase 5) activity. The protein encoded by this gene is localized to the centrosome and Golgi complex, interacts with CDK5R1 and pericentrin (PCNT), plays a role in centriole engagement and microtubule nucleation, and has been linked to primary microcephaly and Alzheimer's disease. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013],
UniProt
Q96SN8
Swiss Prot
Q96SN8
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human CDK5RAP2. AA range:251-300
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Golgi apparatus . Cytoplasm . Cytoplasm, cytoskeleton . Found in the pericentriolar region adhering to the surface of the centrosome and in the region of the centrosomal appendages. Localizes to microtubule plus ends in the presence of EB1/MAPRE1. Localization to centrosomes versus Golgi apparatus may be cell type-dependent. For instance, in SK-BR-3 and HEK293F cells, localizes to centrosomes but not to the Golgi apparatus (PubMed:29162697) . .
Other Product Names
CDK5RAP2; CEP215; KIAA1633; CDK5 regulatory subunit-associated protein 2; CDK5 activator-binding protein C48; Centrosome-associated protein 215
Gene ID (Human)
55755

Related Products

CatalogName
ES6553-01CDK5 Activator-binding C42 rabbit pAb
ES4439-01Cdk5 rabbit pAb
ES4438-01Cdk5 (phospho Tyr15) rabbit pAb
ES8853-01Cdk5 Rabbit Polyclonal Antibody
EA194-01EEF1A2 binding protein Rabbit pAb
ES20768-01EEF1A2 binding protein rabbit pAb
EA252-01EEF1A2 binding protein Rabbit pAb
ES9030-01CDKL5 rabbit pAb
ES1943-01Cdk7 rabbit pAb
ES3928-01Cdk4 rabbit pAb

Alternative Products

CatalogName
E28PT0836CDK5 Activator-binding C42 Rabbit Polyclonal Antibody
APRab08566-01CDK5 Activator-binding C48 Rabbit Polyclonal Antibody
PA89957HU-01Rabbit Anti-Human CDK5 Activator-binding C42 Polyclonal Antibody
PAV5896Rabbit Anti-CDK5 Activator-binding C42/CDK5RAP1 Polyclonal Antibody
PAV5897Rabbit Anti-CDK5 Activator-binding C48/CDK5RAP2 Polyclonal Antibody
PA90122HU-01Rabbit Anti-Human CDK5 Activator-binding C48 Polyclonal Antibody
NBP2-92622-0.1mLRabbit Polyclonal CDK5 Activator 1 Antibody
310235-01CDK5 Activator-binding C42
310236-01CDK5 Activator-binding C48
C12191-01CDK5 Activator-binding C48 Antibody

Popular Products