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PLC β2 rabbit pAb

CAT: 0855-ES6603-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES6603-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H (2) O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol., cofactor:Binds 1 calcium ion per subunit., function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes., miscellaneous:The receptor-mediated activation of PLC-beta-2 is most effectively mediated by one G-protein alpha subunit, alpha-16., similarity:Contains 1 C2 domain., similarity:Contains 1 PI-PLC X-box domain., similarity:Contains 1 PI-PLC Y-box domain., subunit:Interacts with RAC1.
Description
Catalytic activity: 1-phosphatidyl-1D-myo-inositol 4, 5-bisphosphate + H (2)O = 1D-myo-inositol 1, 4, 5-trisphosphate + diacylglycerol. Cofactor: Binds 1 calcium ion per subunit. function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. miscellaneous: The receptor-mediated activation of PLC-beta-2 is most effectively mediated by one G-protein alpha subunit, alpha-16. similarity: Contains 1 C2 domain. similarity: Contains 1 PI-PLC X-box domain. similarity: Contains 1 PI-PLC Y-box domain. subunit: Interacts with RAC1.
UniProt
Q00722
Swiss Prot
Q00722
Reactivity
Human; Mouse; Rat
Immunogen
Synthesized peptide derived from the Internal region of human PLC β2.
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC
Concentration
1 mg/ml
Dilution
WB 1:500-2000; IHC-p 1:50-300
Molecular Weight
150kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
150kD
Fragment
IgG
Subcellular Location
Intracellular, cytosol
Other Product Names
PLCB2; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase beta-2; Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2
Gene ID (Human)
5330

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