PLC β2 rabbit pAb

• Background:

  Catalytic activity:1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H (2) O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol., cofactor:Binds 1 calcium ion per subunit., function:The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes., miscellaneous:The receptor-mediated activation of PLC-beta-2 is most effectively mediated by one G-protein alpha subunit, alpha-16., similarity:Contains 1 C2 domain., similarity:Contains 1 PI-PLC X-box domain., similarity:Contains 1 PI-PLC Y-box domain., subunit:Interacts with RAC1.

• Description:

  Catalytic activity: 1-phosphatidyl-1D-myo-inositol 4, 5-bisphosphate + H (2)O = 1D-myo-inositol 1, 4, 5-trisphosphate + diacylglycerol. Cofactor: Binds 1 calcium ion per subunit. function: The production of the second messenger molecules diacylglycerol (DAG) and inositol 1, 4, 5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. miscellaneous: The receptor-mediated activation of PLC-beta-2 is most effectively mediated by one G-protein alpha subunit, alpha-16. similarity: Contains 1 C2 domain. similarity: Contains 1 PI-PLC X-box domain. similarity: Contains 1 PI-PLC Y-box domain. subunit: Interacts with RAC1.

• UniProt:

  Q00722

• Swiss Prot:

  Q00722

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Synthesized peptide derived from the Internal region of human PLC β2.

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; IHC

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000; IHC-p 1:50-300

• Molecular Weight:

  150kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  150kD

• Fragment:

  IgG

• Subcellular Location:

  Intracellular, cytosol

• Other Product Names:

  PLCB2; 1-phosphatidylinositol 4; 5-bisphosphate phosphodiesterase beta-2; Phosphoinositide phospholipase C-beta-2; Phospholipase C-beta-2; PLC-beta-2

• Gene ID (Human):

  5330