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CNOT2 (phospho Ser101) rabbit pAb

CAT: 0855-ES6403-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES6403-01Size:50 µL
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Background
CCR4-NOT transcription complex subunit 2 (CNOT2) Homo sapiens This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
Description
CCR4-NOT transcription complex subunit 2 (CNOT2) Homo sapiens This gene encodes a subunit of the multi-component CCR4-NOT complex. The CCR4-NOT complex regulates mRNA synthesis and degradation and is also thought to be involved in mRNA splicing, transport and localization. The encoded protein interacts with histone deacetylases and functions as a repressor of polymerase II transcription. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010],
UniProt
Q9NZN8
Swiss Prot
Q9NZN8
Reactivity
Human; Mouse; Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human CNOT2 around the phosphorylation site of Ser101. AA range:67-116
Clonality
Polyclonal
Source
Rabbit
Applications
IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Storage Conditions
-20°C/1 year
Fragment
IgG
Subcellular Location
Cytoplasm . Nucleus .
Other Product Names
CNOT2; CDC36; NOT2; HSPC131; MSTP046; CCR4-NOT transcription complex subunit 2; CCR4-associated factor 2
Gene ID (Human)
4848

UniProtKB · Q9NZN8

CCR4-NOT transcription complex subunit 2

CNOT2_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q9NZN8
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CNOT2
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q9H3E0, Q9NSX5, Q9NWR6, Q9P028
Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

Molecular function

Developmental proteinRepressor

Disease

Disease variantIntellectual disability

PTM

Phosphoprotein

Biological process

RNA-mediated gene silencingTranscriptionTranscription regulationTranslation regulation

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