MuSK (phospho Tyr755) rabbit pAb

MuSK (phospho Tyr755) rabbit pAb

• Description: This gene encodes a muscle-specific tyrosine kinase receptor. The encoded protein may play a role in clustering of the acetylcholine receptor in the postsynaptic neuromuscular junction. Mutations in this gene have been associated with congenital myasthenic syndrome. Alternatively spliced transcript variants have been described. [provided by RefSeq, Oct 2009],
• Synonyms: MUSK; Muscle; skeletal receptor tyrosine-protein kinase; Muscle-specific tyrosine-protein kinase receptor; MuSK; Muscle-specific kinase receptor
• Gene ID: 4593
• UniProt: O15146
• Cellular Locus: Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein. Colocalizes with acetylcholine receptors (AChR) to the postsynaptic cell membrane of the neuromuscular junction..
• Host: Rabbit
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Synthesized phospho-peptide around the phosphorylation site of human MuSK (phospho Tyr755)
• Clonality: Polyclonal
• Validated Applications: WB, ELISA, IHC
• Stability: 1 year
• Concentration: 1 mg/mL
• Dilution: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
• Molecular Weight: 97kD
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.