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Olfactory receptor 52A4 rabbit pAb

CAT: 0855-ES6045-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES6045-01Size:50 µL
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Background
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. Although originally considered to be a functional olfactory receptor, this family member is now considered to be pseudogene due to the presence of a C-terminal frameshift compared to other family memb
Description
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. Although originally considered to be a functional olfactory receptor, this family member is now considered to be pseudogene due to the presence of a C-terminal frameshift compared to other family memb
UniProt
A6NMU1
Swiss Prot
A6NMU1
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human OR52A4. AA range:211-260
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
35kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
35kD
Fragment
IgG
Subcellular Location
Cell membrane; Multi-pass membrane protein.
Other Product Names
OR52A4; Putative olfactory receptor 52A4
Gene ID (Human)
390053

UniProtKB · A6NMU1

Olfactory receptor 52A4

O52A4_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
A6NMU1
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
OR52A4P
Protein existence
2: Evidence at transcript level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
B9EIN7
Protein keywords

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoprotein

Molecular function

G protein-coupled receptorReceptorTransducer

Biological process

OlfactionSensory transduction

Technical term

Reference proteome

Domain

TransmembraneTransmembrane helix

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