IL-4 rabbit pAb

• Background:

  The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells. This cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]

• Description:

  The protein encoded by this gene is a pleiotropic Cytokine produced by activated T cells. This Cytokine is a ligand for interleukin 4 receptor. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this Cytokine and IL13. STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine. This gene, IL3, IL5, IL13, and CSF2 form a Cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13. This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008],

• UniProt:

  P05112

• Swiss Prot:

  P05112

• Reactivity:

  Human; Mouse

• Immunogen:

  Synthesized peptide derived from the C-terminal region of human IL-4.

• Clonality:

  Polyclonal

• Source:

  Rabbit

• Applications:

  WB; Flow Cyt; ELISA

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500-2000; Flow Cyt 1:50-200; ELISA 1:5000-20000

• Molecular Weight:

  18kD

• Storage Conditions:

  -20°C/1 year

• Observed Molecular Weight:

  18kD

• Fragment:

  IgG

• Subcellular Location:

  Secreted.

• Other Product Names:

  IL4; Interleukin-4; IL-4; B-cell stimulatory factor 1; BSF-1; Binetrakin; Lymphocyte stimulatory factor 1; Pitrakinra

• Gene ID (Human):

  3565