SPDMV

• Description:

  SPDMV is a glutathione cleavable ADC linker used for the antibody-drug conjugate (ADCs) [1].

• UNSPSC:

  12352203

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/spdmv.html

• Purity:

  99.16

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  CC(SSC1=NC=CC=C1)(C)CCC(ON2C(CCC2=O)=O)=O

• Molecular Formula:

  C15H18N2O4S2

• Molecular Weight:

  354.44

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Daniel Teufel, et al. Bicyclic peptide-toxin conjugates specific for mt1-mmp. WO2017191460A1.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, sealed storage, away from moisture)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  Disulfide Cleavable Linker

• CAS Number:

  [890409-85-5]