E-Ras rabbit pAb

• Background :

  This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012]

• Description :

  This gene encodes a constitutively active member of the small GTPase Ras protein family. The encoded protein activates the phosphatidylinositol 3-kinase signal transduction pathway in undifferentiated stem cells, but is not expressed in differentiated cells. This gene may be involved in cancer and chemotherapy resistance. [provided by RefSeq, Dec 2012],

• UniProt :

  Q7Z444

• Swiss Prot :

  Q7Z444

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human ERAS. AA range:184-233

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight :

  25kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  25kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Lipid-anchor ; Cytoplasmic side .

• Other Product Names :

  ERAS; HRAS2; HRASP; GTPase ERas; E-Ras; Embryonic stem cell-expressed Ras

• Gene ID (Human) :

  3266