HDAC1 (phospho Ser421) rabbit pAb
CAT:
855-ES5729-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
HDAC1 (phospho Ser421) rabbit pAb
- Description: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008],
- Synonyms: HDAC1; RPD3L1; Histone deacetylase 1; HD1
- Gene ID: 3065
- UniProt: Q13547
- Cellular Locus: Nucleus.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: The antiserum was produced against synthesized peptide derived from human HDAC1 around the phosphorylation site of Ser421. AA range:387-436
- Clonality: Polyclonal
- Validated Applications: WB, IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
- Molecular Weight: 62kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.