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GPR132 rabbit pAb

CAT: 0855-ES5700-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5700-01Size:50 µL
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Background
This gene encodes a member of the guanine nucleotide-binding protein (G protein) -coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
Description
This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor (GPCR) superfamily. The receptors are seven-pass transmembrane proteins that respond to extracellular cues and activate intracellular signal transduction pathways. This protein was reported to be a receptor for lysophosphatidylcholine action, but PubMedID: 15653487 retracts this finding and instead suggests this protein to be an effector of lysophosphatidylcholine action. This protein may have proton-sensing activity and may be a receptor for oxidized free fatty acids. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],
UniProt
Q9UNW8
Swiss Prot
Q9UNW8
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human GPR132. AA range:311-360
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Molecular Weight
42kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
42kD
Fragment
IgG
Subcellular Location
Cell membrane ; Multi-pass membrane protein . Internalized and accumulated in endosomal compartments. LPC triggers the relocalization from the endosomal compartment to the cell surface (By similarity) . .
Other Product Names
GPR132; G2A; Probable G-protein coupled receptor 132; G2 accumulation protein
Gene ID (Human)
29933

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