GPR17 rabbit pAb

• Background:

  Function:Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs) . Signals through G (i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia., similarity:Belongs to the G-protein coupled receptor 1 family., tissue specificity:Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.

• Description:

  Function: Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G (i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia. similarity: Belongs to the G-protein coupled receptor 1 family. tissue specificity: Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain.

• Synonyms:

  GPR17; Uracil nucleotide/cysteinyl leukotriene receptor; UDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12

• Gene ID:

  2840

• UniProt:

  Q13304

• Cellular Locus:

  Cell membrane; Multi-pass membrane protein.

• Host:

  Rabbit

• Species Reactivity:

  Human, Mouse, Rat

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  The antiserum was produced against synthesized peptide derived from human GPR17. AA range:196-245

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Source:

  Rabbit

• Applications:

  WB, IF, ELISA

• Validated Applications:

  WB, IF, ELISA

• Stability:

  -20°C/1 year

• Concentration:

  1 mg/mL

• Dilution:

  Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

• Molecular Weight:

  59kD

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

• Observed Molecular Weight:

  59 kD

• Subcellular Location:

  Cell membrane; Multi-pass membrane protein.

• Other Product Names:

  GPR17; Uracil nucleotide/cysteinyl leukotriene receptor; UDP/CysLT receptor; G-protein coupled receptor 17; P2Y-like receptor; R12

• Gene ID (Human):

  2840

• SwissProt (Human):

  Q13304