Cadherin-20 rabbit pAb
CAT:
855-ES5578-02
Size:
100 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Cadherin-20 rabbit pAb
- Description: This gene is a type II classical cadherin from the cadherin superfamily and one of three cadherin 7-like genes located in a cluster on chromosome 18. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Since disturbance of intracellular adhesion is a prerequisite for invasion and metastasis of tumor cells, cadherins are considered prime candidates for tumor suppressor genes. [provided by RefSeq, Jul 2008],
- Synonyms: CDH20; CDH7L3; Cadherin-20
- Gene ID: 28316
- UniProt: Q9HBT6
- Cellular Locus: Cell membrane; Single-pass type I membrane protein.
- Host: Rabbit
- Species Reactivity: Human, Mouse, Rat
- Immunogen: The antiserum was produced against synthesized peptide derived from human CDH20. AA range:111-160
- Clonality: Polyclonal
- Validated Applications: IHC, IF, ELISA
- Stability: 1 year
- Concentration: 1 mg/mL
- Dilution: Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.