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MIP-T3 rabbit pAb

CAT: 0855-ES5467-01Size: 50 µLDry Ice: NoHazardous: No
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CAT#:0855-ES5467-01Size:50 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Function:Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules., similarity:Belongs to the TRAF3IP1 family., subcellular location:Microtubules., subunit:Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1., tissue specificity:Ubiquitous.
Description
Function: Play an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. similarity: Belongs to the TRAF3IP1 family. subcellular location: Microtubules. subunit: Interacts with IL13RA1. Binds to microtubules, TRAF3 and DISC1. tissue specificity: Ubiquitous.
UniProt
Q8TDR0
Swiss Prot
Q8TDR0
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human MIPT3. AA range:221-270
Clonality
Polyclonal
Source
Rabbit
Applications
WB; IHC; IF; ELISA
Concentration
1 mg/ml
Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Molecular Weight
78kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
78kD
Fragment
IgG
Subcellular Location
Cytoplasm, cytoskeleton . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, cilium basal body . Microtubules (PubMed:12935900) . In the cilium, it is observed at the ciliary base, ciliary transition zone and ciliary tip (PubMed:26487268) . .
Other Product Names
TRAF3IP1; MIPT3; TRAF3-interacting protein 1; Interleukin-13 receptor alpha 1-binding protein 1; Microtubule-interacting protein associated with TRAF3; MIP-T3
Gene ID (Human)
26146

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