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CYP4X1 rabbit pAb

CAT: 0855-ES5460-01Size: 50 µLDry Ice: NoHazardous: No
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Background
This gene encodes a member of the cytochrome P450 superfamily of enzymes and is located within a cluster of genes belonging to this superfamily on chromosome 1. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]
Description
This gene encodes a member of the Cytochrome P450 superfamily of enzymes and is located within a cluster of genes belonging to this superfamily on chromosome 1. The Cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016],
Product Name Alternative
CYP4X1; Cytochrome P450 4X1; CYPIVX1
UniProt
Q8N118
Swiss Prot
Q8N118
Reactivity
Human; Rat; Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human Cytochrome P450 4X1. AA range:231-280
Target
CYP4X1
Clonality
Polyclonal
Source
Rabbit
Applications
WB; ELISA
Concentration
1 mg/ml
Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Buffer
-20°C/1 year
Molecular Weight
60kD
Storage Conditions
-20°C/1 year
Observed Molecular Weight
60kD
Fragment
IgG
Subcellular Location
Endoplasmic reticulum membrane ; Single-pass membrane protein . Microsome membrane ; Single-pass membrane protein .
Other Product Names
CYP4X1; Cytochrome P450 4X1; CYPIVX1
Gene ID (Human)
260293

UniProtKB · Q8N118

Cytochrome P450 4X1

CP4X1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q8N118
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
CYP4X1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
1.14.14.-
Processing
—
Secondary accessions
G3V1U1, Q5VVE5, Q6ZN67, Q8NAZ3
Protein keywords

Coding sequence diversity

Alternative splicing

Cellular component

Endoplasmic reticulumMembraneMicrosome

Ligand

HemeIronMetal-binding

Biological process

Lipid metabolism

Molecular function

MonooxygenaseOxidoreductase

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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